AND YOU GUYS THOUGHT I WAS KIDDING ABOUT HIS SPINNING EYES. Okay, most of you probably don't even know what I'm talking about, but I'm just sayin' XD
The first part with all the girls is one of the oldest jokes associated with Dwayne between me and ~Apkinesis
It came from when I first created Dwayne in ME2 as I was importing my original maleShep (though I later played as him in ME1). Spin the control stick fast enough in character creation and you can make Shepard's eyes spin!
We deduced that after Cerberus rebuilt him, Dwayne's eyes spin whenever he's very nervous, upset, etc. *nods*
Also, please blame my gif animator for making the colors all wonky. Here's what the original colors are supposed to be like: [link]
I originally sketched this November-ish, then I tweaked it a little bit before coloring
The picture Dwayne's holding is this one, minus the shading, gradients, and textures: [link]
Mass Effect series (c) BioWare